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Compound InformationSONAR Target prediction
Name:

R(-)-Propylnorapomorphine hydrochloride

Unique Identifier:LOPAC 00265
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C19ClH22NO2
Molecular Weight:310.669 g/mol
X log p:10.934  (online calculus)
Lipinksi Failures1
TPSA3.24
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:3
Rotatable Bond Count:2
Canonical Smiles:Cl.CCCN1CCc2cccc3c2C1Cc1ccc(O)c(O)c13
Class:Dopamine
Action:Agonist
Selectivity:DRD2

Found: 14 active | as graph: single | with analogs 1 2 3 4 5 6 7 8 9 10  Next >> 
Species: 4932
Condition: BY4743
Replicates: 2
Raw OD Value: r im 0.5758±0.34429
Normalized OD Score: sc h 0.6750±0.254241
Z-Score: -9.0684±7.37541
p-Value: 0.0000582942
Z-Factor: -1.58011
Fitness Defect: 9.75
Bioactivity Statement: Outlier
Experimental Conditions
Library:Lopac
Plate Number and Position:6|D6
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:0.00 Celcius
Date:2005-08-19 YYYY-MM-DD
Plate CH Control (+):0.046024999999999996±0.00128
Plate DMSO Control (-):0.812075±0.02313
Plate Z-Factor:0.9303
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DBLink | Rows returned: 91 2 Next >> 
30136
30137
43634
43635
167715
450906

internal high similarity DBLink | Rows returned: 4
LOPAC 00266 0.9187
LOPAC 01342 0.9363
SPE01500129 0.9675
LOPAC 00267 0.9812

active | Cluster 1444 | Additional Members: 3 | Rows returned: 2
LOPAC 00266 0.363636363636364
LOPAC 00267 0

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